Acrolein → 2-(4-Methylphenyl)-1-(4-sulfamoylphenyl)pyrrole

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=2)[C:9]#N)=[CH:4][CH:3]=1.[CH:22]([CH:24]=C)=O>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:11]([C:12]3[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=3)[CH:22]=[CH:24][CH:9]=2)=[CH:4][CH:3]=1

参加物

反応物 2

HCID 7847Acrolein

HCID 21862809HCID 21862809、化合物

生成物 1

HCID 218628292-(4-Methylphenyl)-1-(4-sulfamoylphenyl)pyrrole

実験手順

Following a procedure similar to that described in Example 1(iii), but using α-(4-methylphenyl)-α-(4-sulfamoylanilino)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a brown powder (yield 13%), melting at 183-184° C.

出典と根拠

ORDレコード: ord-fcbdbaec14734beb8ea06418f985b35f
出典データセット: uspto-grants-2006_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: USRE039420E1

反応ノート

読み込み中…