Hydrochloric Acid → Sodium Chloride
反応式
[OH:1][CH:2]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)[C:3]([O:5]CC)=[O:4].[OH-].[Na+:15].O.[ClH:17]>C(O)C>[OH:1][CH:2]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)[C:3]([OH:5])=[O:4].[Cl-:17].[Na+:15]参加物
7
実験手順
To a stirred solution of ethyl 2-hydroxy-2-(2-pyridyl)acetate (0.5 g, 2.56 mmol) in ethanol (5 mL) was added 2.0 M NaOH in water (1.4 mL, 2.8 mmol). The resulting solution was stirred at ambient temperature for 18 h. TLC analysis indicated complete consumption of starting ester. 6.0 M HCl in water (0.46 mL, 2.8 mmol) was added and the solvents were removed under reduced pressure and the resulting solid was dried in vacuo for 18 h to give 2-hydroxy-2-(2-pyridyl)acetic acid as a mixture with sodium chloride.
後処理
- customconsumption of starting ester
- customthe solvents were removed under reduced pressure
- customthe resulting solid was dried in vacuo for 18 h
出典と根拠
- ORDレコード
- ord-7c590cc2bf8f47f19eb8af2a7f8e1162
- 出典データセット
- uspto-grants-2006_12
- 特許番号
- US07144899B2
反応ノート
読み込み中…