Ferrous Chloride → HCID 56945463、化合物

HRID 857832ノート

反応式

HRID 857832 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1.[Fe:23]([Cl:25])[Cl:24]>C1COCC1>[Fe:23]([Cl:25])[Cl:24].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1

参加物

4

反応物 2

HCID 24458Ferrous ChlorideHCID 100629331-(pyridin-2-yl)-N-((1R,2R)-2-(((pyridin-2-yl)methylidene)amino)cyclohexyl)methanimine

生成物 1

HCID 56945463HCID 56945463、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

In a baked Schlenk tube, 1.0 g (3.4 mmol) of trans-N,N′-bispyridin-2-ylmethylenecyclohexane-1,2-diamine are dissolved in 40 ml of THF and admixed with 431 mg (3.4 mmol) of iron(II) chloride (anhydrous). After 0.5 h, the solution becomes dark blue. After stirring at room temperature for another 2 hours, the solvent is removed under reduced pressure and the residue is stirred with 10 ml of heptane. Filtration through a G3 frit gives the product as a dark blue solid in a yield of 1.41 g (3.36 mmol, 99%).

後処理

  1. customthe solvent is removed under reduced pressure
  2. stirringthe residue is stirred with 10 ml of heptane
  3. filtrationFiltration through a G3 frit

出典と根拠

ORDレコード
ord-f89c31fc201c4952aada0bfe7c6bcd77
出典データセット
uspto-grants-2006_12
特許番号
US07148174B2

反応ノート

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