Chlorosulfonic acid → HCID 58762874、化合物

反応式

[CH3:1][C:2]1[C:10]2[O:9][C:8](=[O:11])[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.Cl[S:13]([OH:16])(=[O:15])=[O:14]>>[CH3:1][C:2]1[C:10]2[O:9][C:8](=[O:11])[NH:7][C:6]=2[CH:5]=[CH:4][C:3]=1[S:13]([OH:16])(=[O:15])=[O:14]

参加物

反応物 2

HCID 24638Chlorosulfonic acid

HCID 117447917-methyl-3H-benzooxazol-2-one

生成物 1

HCID 58762874HCID 58762874、化合物収率 60%

実験手順

7-Methyl-3H-benzooxazol-2-one [5.0 g, 33 mmol, prepared according to the procedure described in J. Org. Chem. (1982), 47(14), 2804–6) was treated with chlorosulphonic acid as described in Example 15 (i) to give the title compound as an off-white solid (4.5 g, 60%).

出典と根拠

ORDレコード: ord-c3aeb38733d7405a88f0b9ff2a424dc2
出典データセット: uspto-grants-2006_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07148236B2

反応ノート

読み込み中…