Iodoethane → 1-Ethoxy-3-fluorobenzene
反応式
[F:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[CH2:9](I)[CH3:10].C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[CH2:9]([O:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=1)[CH3:10]参加物
5
実験手順
3-Fluorophenol (20.0 g, 178.4 mmol), ethyl iodide (83.5 g, 535.2 mmol) and K2CO3 (49.3 g, 356.8 mmol) in 250 ml of acetone were stirred at 50° C. overnight. The mixture was filtered and evaporated to give 1-ethoxy-3-fluorobenzene.
後処理
- filtrationThe mixture was filtered
- customevaporated
出典と根拠
- ORDレコード
- ord-285479cd4a8d4ddcacd5bbf1532b7b81
- 出典データセット
- uspto-grants-1998_02
- 特許番号
- US05714503
反応ノート
読み込み中…