Hydrazine hydrate (1:1) → Diethyl [(6-amino-3-chloro-2-pyridinyl)methyl]phosphonate
反応式
[Cl:1][C:2]1[C:3]([CH2:19][P:20](=[O:27])([O:24][CH2:25][CH3:26])[O:21][CH2:22][CH3:23])=[N:4][C:5]([N:8]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:6][CH:7]=1.O.NN>C(Cl)Cl>[NH2:8][C:5]1[N:4]=[C:3]([CH2:19][P:20](=[O:27])([O:24][CH2:25][CH3:26])[O:21][CH2:22][CH3:23])[C:2]([Cl:1])=[CH:7][CH:6]=1参加物
4
実験手順
Following the procedure from Example 16, the product from Example 27 (1.0 g, 2.4 mmol) was reacted with hydrazine monohydrate (0.121 g, 2.4 mmol) in CH2Cl2 (25 mL). Workup produced the crude title product which was used without further purification.
出典と根拠
- ORDレコード
- ord-1a8aca07cf36418c929108cb02a5ad2d
- 出典データセット
- uspto-grants-1998_02
- 特許番号
- US05716964
反応ノート
読み込み中…