Benzaldehyde → 4-Benzylamino-1-Butanol

HRID 862781ノート

反応式

HRID 862781 の反応式
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6].[CH:7](=O)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>O=[Pt]=O.CCO>[C:8]1([CH2:7][NH:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

5

反応物 2

HCID 240BenzaldehydeHCID 258684-Amino-1-butanol

生成物 1

HCID 17900184-Benzylamino-1-Butanol

試薬・触媒・溶媒 2

HCID 345198Adams' catalyst触媒HCID 702Ethanol溶媒

実験手順

Combine 4-amino-butan-1-ol (8.9 gm-0.1 mol), benzaldehyde (10.6 gm-0.1 mol), EtOH (100 ml) and PtO2 (0.3 gm), and hydrogenate the mixture at 45 lbs./sq.in. until H2 is no longer taken up. Filter, evaporate the solvent (in vacuo) to yield 17.7 gm of the desired compound. Rf is 0.70 (eluted from silica gel with 10% conc. NH3 /CH3OH).

後処理

  1. filtrationFilter
  2. customevaporate the solvent (in vacuo)

出典と根拠

ORDレコード
ord-903fe23eb0b0453cbd0c0b252b58ca0a
出典データセット
uspto-grants-1998_02
特許番号
US05719193

反応ノート

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