Ethanolamine → HCID 54468234、化合物
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][CH2:10][O:11][N:12]2C(=O)C3=CC=CC=C3C2=O)=[CH:4][CH:3]=1.C(CN)O>ClCCl>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][CH2:10][O:11][NH2:12])=[CH:6][CH:7]=1参加物
4
反応条件
- 温度
- 30 °C
実験手順
33.4 g (0.093 mol) of N-[3-(4-bromophenyl)-prop-2-enyloxy]-phthalimide were introduced a little at a time into 50 ml of ethanolamine; the temperature increased to 30° C. After stirring had been carried out for two hours at 60° C., the mixture was allowed to cool and 200 ml of dichloromethane were added to it. It was extracted by shaking with iced water. The organic phase was dried and evaporated down and the residue was crystallized from petroleum ether. 20.2 g (95.3% of theory) of 3-(4-bromophenyl)-prop-2-enyloxyamine of melting point 35°-38° C. were obtained.
後処理
- temperatureto cool
- extractionIt was extracted
- stirringby shaking with iced water
- customThe organic phase was dried
- customevaporated down
- customthe residue was crystallized from petroleum ether
出典と根拠
- ORDレコード
- ord-e95b325da54f4240808b57cbe4101d8b
- 出典データセット
- uspto-grants-1996_10
- 特許番号
- US05563114
反応ノート
読み込み中…