Diethyl Ether → N-(5-bromo-3-pyridyl)-N'-cyano-N"-(2-phenylthioethyl)guanidine
反応式
CS[C:3](=[N:12][C:13]#[N:14])[NH:4][C:5]1[CH:6]=[N:7][CH:8]=[C:9]([Br:11])[CH:10]=1.[C:15]1([S:21][CH2:22][CH2:23][NH2:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.CCOCC>N1C=CC=CC=1>[Br:11][C:9]1[CH:10]=[C:5]([NH:4][C:3]([NH:12][C:13]#[N:14])=[N:24][CH2:23][CH2:22][S:21][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[N:7][CH:8]=1参加物
5
実験手順
S-Methyl N-(5-bromo-3-pyridyl)-N'-cyanoisothiourea (650 mg) and 2-phenylthioethylamine (740 mg) in pyridine (0.5 ml) were heated to 50° C. for 5 hours. To the resulting clear solution was added ether (10 ml), and the desired pure compound was collected by filtration and washed with ether.
後処理
- filtrationthe desired pure compound was collected by filtration
- washwashed with ether
出典と根拠
- ORDレコード
- ord-262f92ccf08e488884e77e502fc46488
- 出典データセット
- uspto-grants-1996_10
- 特許番号
- US05563160
反応ノート
読み込み中…