Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 865138ノート

反応式

HRID 865138 の反応式
[Cl:1][C:2]1[C:6]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:5][S:4][N:3]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:6]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:5][S:4][N:3]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

生成物 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide収率 100.1%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A solution of 3-(3-chloro-1,2,5-thiadiazol-4-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100% ) of the title compound.

後処理

  1. filtrationThe precipitate was collected by filtration

出典と根拠

ORDレコード
ord-86853656ed5f45bf920a9ed8060dbc3a
出典データセット
uspto-grants-1996_10
特許番号
US05565475

反応ノート

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