Methyl iodide → 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

HRID 865195ノート

反応式

HRID 865195 の反応式
[NH2:1][C:2]1[C:6]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:5][O:4][N:3]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[NH2:1][C:2]1[C:6]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:5][O:4][N:3]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 14155234-Pyridin-3-yl-1,2,5-oxadiazol-3-amine

生成物 1

HCID 190753223-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of 3-(3-amino-1,2,5-oxadiazol-4-yl)pyridine (870 mg, 5.3 mmol) in acetone (20 ml) was added methyl iodide (990 μl, 16 mmol) and the reaction mixture was stirred overnight at room temperature. The title compound precipitated and was collected by filtration (1.1 g, 69%).

後処理

  1. customThe title compound precipitated
  2. filtrationwas collected by filtration (1.1 g, 69%)

出典と根拠

ORDレコード
ord-d1ad5561e8cf48c7bc5ec2645c212e27
出典データセット
uspto-grants-1996_10
特許番号
US05565475

反応ノート

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