関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Boron tribromide | HCID 25134 | — |
| 反応物 | 2,3-Dihydro-5-methoxy-1,4-benzodioxin | HCID 74371 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2,3-Dihydro-1,4-benzodioxin-5-ol | HCID 82520 | — |
反応手順
At 0° C., boron tribromide (5.6 cm3) is added slowly to a solution of 5-methoxy-1,4-benzodioxane (5 g, 30.1 mmol) in 25 cm3 of CH2Cl2. The mixture is stirred at 0° C. for 15 min, the solution is then hydrolysed with 10 cm3 of water and the product is extracted with CH2Cl2. Purification on a silica column (eluent: 100% CH2Cl2) enables 4.49 g of a colorless oil to be obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05569669 |
|---|
| 出典データセット | uspto-grants-1996_10 |
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| ORD ID | ord-ce06de15ee3d4369a4a6f27e4b83b51b |
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| 出典メモ | uspto-grants-1996_10 |
|---|
