Diethyl Ether → 2-Bromoethyl ethanesulfonate
反応式
[Br:1][CH2:2][CH2:3][OH:4].[CH2:5]([S:7](Cl)(=[O:9])=[O:8])[CH3:6].CCOCC>C(N(CC)CC)C>[CH2:5]([S:7]([O:4][CH2:3][CH2:2][Br:1])(=[O:9])=[O:8])[CH3:6]参加物
5
実験手順
A mixture containing 12.5 ml. of 2-bromoethanol, 12.9 ml. of ethane sulfonyl chloride and 100 ml. of ether was formed. Then, 14 ml. of triethylamine was added dropwise over a 55 minute period at 5°-10° C. and stirred for 1 hour. The mixture was allowed to come to room temperature and stirred for an additional 15 minutes. To the mixture was added 100 ml. of water, the ether layer was separated, dried over magnesium sulfate and evaporated to yield 17.6 grams of a yellow oil. nD30 1.4760.
後処理
- additionA mixture containing 12.5 ml
- customto come to room temperature
- stirringstirred for an additional 15 minutes
- additionTo the mixture was added 100 ml
- customof water, the ether layer was separated
- dry with materialdried over magnesium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-184884f6af584f4fa7fe43a258fba8e5
- 出典データセット
- uspto-grants-1978_07
- 特許番号
- US04098599
反応ノート
読み込み中…