Formaldehyde → HCID 54405233、化合物

反応式

[NH2:1][C:2]([P:8]([OH:11])(=[O:10])[OH:9])([P:4]([OH:7])(=[O:6])[OH:5])[CH3:3].C=O.P(Cl)(Cl)Cl>>[P:4]([CH:2]=[N:1][C:2]([P:4]([OH:7])(=[O:5])[OH:6])([P:8]([OH:11])(=[O:9])[OH:10])[CH3:3])([OH:7])([OH:6])=[O:5]

参加物

反応物 3

HCID 712Formaldehyde

HCID 24387Phosphorus trichloride

HCID 84770(1-Aminoethylidene)bisphosphonic acid

生成物 1

HCID 54405233HCID 54405233、化合物

実験手順

103 g. of 1-amino ethane-1,1-diphosphonic acid are suspended in 100 g. of a 30% formaldehyde solution. 85 cc. of phosphorus trichloride are added thereto drop by drop while stirring. After the addition is completed, the mixture is heated to boiling until a homogeneous mixture is formed. The water is removed by evaporation in a vacuum. The resulting phosphonic acid mixture is precipitated by the addition of acetone. N-phosphono methylene-1-amino ethane-1,1-diphosphonic acid is obtained in this manner.

後処理

additionAfter the addition
temperaturethe mixture is heated
customis formed
customThe water is removed by evaporation in a vacuum
customThe resulting phosphonic acid mixture is precipitated by the addition of acetone

出典と根拠

ORDレコード: ord-1424e06f291248e488103bc1c490419e
出典データセット: uspto-grants-1978_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04098814

反応ノート

読み込み中…

参加物