Water → HCID 20382795、化合物

HRID 866524

反応式

HRID 866524 の反応式
[C:1]1(=[O:7])O[C:4](=[O:5])[CH2:3][CH2:2]1.[C:8]([NH:14][NH2:15])(=[O:13])[C:9]([NH:11][NH2:12])=[O:10].CN1[CH2:21][CH2:20][CH2:19][C:18]1=[O:22].C1(C)C=CC=CC=1.[OH2:30]>>[C:18]1(=[O:22])[N:12]([NH:11][C:9]([C:8]([NH:14][N:15]2[C:1](=[O:7])[CH2:2][CH2:3][C:4]2=[O:5])=[O:13])=[O:10])[C:21](=[O:30])[CH2:20][CH2:19]1

参加物

6

反応物 5

HCID 962WaterHCID 1140TolueneHCID 7922Succinic anhydrideHCID 13387N-methyl-2-pyrrolidoneHCID 13826Oxalic acid, dihydrazide

生成物 1

HCID 20382795HCID 20382795、化合物収率 49%

実験手順

Two moles (200 g.) of succinic anhydride and one mole (118 g.) of oxalic dihydrazide in 750 ml. N-methyl-2-pyrrolidone and 500 ml. toluene were heated at reflux until water evolution was complete (about 4 hours). Upon cooling, a crystalline complex separated. The mixture was diluted with benzene and then filtered. After drying at 50° C, the complex was treated with water to give N,N'-bis(succinimido)oxamide, having a melting point of >310° C. The overall yield was about 49%.

後処理

  1. custom(about 4 hours)
  2. temperatureUpon cooling
  3. customa crystalline complex separated
  4. additionThe mixture was diluted with benzene
  5. filtrationfiltered
  6. customAfter drying at 50° C
  7. additionthe complex was treated with water

出典と根拠

ORDレコード
ord-87418fde660d413491dd8ff98aee3fdb
出典データセット
uspto-grants-1978_07
特許番号
US04100132

関連ノート

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