Hydrochloric Acid → HCID 54467230、化合物

HRID 868358

反応式

HRID 868358 の反応式
Cl.[OH:2][C:3]1[C:4]([CH3:18])=[N:5][CH:6]=[C:7]([CH2:16][OH:17])[C:8]=1[CH:9]=[CH:10][C:11]([O:13]CC)=[O:12].Cl>[OH-].[Na+]>[OH:2][C:3]1[C:4]([CH3:18])=[N:5][CH:6]=[C:7]([CH2:16][OH:17])[C:8]=1[CH:9]=[CH:10][C:11]([OH:13])=[O:12]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 67938271Ethyl 3-(3-hydroxy-5-hydroxymethyl-2-methyl-4-pyridyl)acrylate hydrochloride

生成物 1

HCID 54467230HCID 54467230、化合物収率 95.9%

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒

実験手順

A mixture of 3.0 g of ethyl 3-(3-hydroxy-5-hydroxymethyl-2-methyl-4-pyridyl)acrylate hydrochloride in 15 ml of 1N aqueous sodium hydroxide solution is stirred at room temperature for 1 hour. The reaction mixture is adjusted to pH 4 with 10% hydrochloric acid, and the resulting precipitate is collected to give 2.2 g of 3-(3-hydroxy-5-hydroxymethyl-2-methyl-4-pyridyl)acrylic acid.

後処理

  1. customthe resulting precipitate is collected

出典と根拠

ORDレコード
ord-9fdfaace917c40dda78e7076ec6cc837
出典データセット
uspto-grants-1988_10
特許番号
US04778796

関連ノート

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