Semicarbazide hydrochloride → HCID 178422414、化合物

反応式

[Br:1][C:2]1[CH:3]=[C:4]([CH3:22])[CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][N:13]([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])[C:8](=[O:20])[C:7]2=O.Cl.[NH2:24][NH:25][C:26]([NH2:28])=[O:27]>>[Br:1][C:2]1[CH:3]=[C:4]([CH3:22])[CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][N:13]([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])[C:8](=[O:20])/[C:7]/2=[N:24]/[NH:25][C:26]([NH2:28])=[O:27]

参加物

反応物 2

HCID 11236Semicarbazide hydrochloride

HCID 13934419HCID 13934419、化合物

生成物 1

HCID 178422414HCID 178422414、化合物収率 87.9%

実験手順

By using 7-bromo-1-(2-diisopropylaminoethyl)-5-methylisatin and semicarbazide hydrochloride, a method analogous to that described in Example 4 was carried out to obtain (E)-7-bromo-1-(2-diisopropylaminoethyl)-5-methylisatin 3-semicarbazone having a melting point of 189°-192° C. (yield: 87.9%, recrystallizing solvent: chloroform-hexane)

出典と根拠

ORDレコード: ord-7fa56d7f977b4dfa9596d1a74cec2539
出典データセット: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04780477

反応ノート

読み込み中…