Semicarbazide hydrochloride → HCID 178457375、化合物

反応式

[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[NH2:19][NH:20][C:21]([NH2:23])=[O:22]>>[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)/[C:10](=[N:19]\[NH:20][C:21]([NH2:23])=[O:22])/[C:8]1=[O:9])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 11236Semicarbazide hydrochloride

HCID 21287238HCID 21287238、化合物

生成物 1

HCID 178457375HCID 178457375、化合物収率 49.8%

実験手順

By using 1-(2-isopropylaminoethyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out, and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-isopropylaminoethyl)isatin 3-semicarbazone having a melting point of 169°-172° C. (decomposition) (yield: 49.8%).

後処理

customthe reaction product was recrystallized from ethanol

出典と根拠

ORDレコード: ord-ec806857fa414720b0039066eb587a42
出典データセット: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04780477

反応ノート

読み込み中…

参加物