Trifluoroacetic acid → 6-Chloro-5-methylpyridazin-3-amine
反応式
[Cl:1][C:2]1[N:7]=[N:6][C:5]([NH:8]CC2C=CC(OC)=CC=2OC)=[CH:4][C:3]=1[CH3:20].C(O)(C(F)(F)F)=O>C(Cl)Cl>[Cl:1][C:2]1[N:7]=[N:6][C:5]([NH2:8])=[CH:4][C:3]=1[CH3:20]参加物
4
実験手順
To a solution of (6-chloro-5-methyl-pyridazin-3-yl)-(2,4-dimethoxy-benzyl)-amine from above (680 mg) in DCM (8 ml) was added TFA (8 ml). The resulting solution was allowed to stand for overnight. The mixture was concentrated to give the titled compound which was used directly for next step.
後処理
- concentrationThe mixture was concentrated
出典と根拠
- ORDレコード
- ord-4179f113de524718b26d2b53cccacf59
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08969565B2
反応ノート
読み込み中…