Isopropyl iodide → 9H-Fluorene, 9-(1-methylethyl)-

HRID 871192ノート

反応式

HRID 871192 の反応式
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16][CH2:17]C.IC(C)C.OC1O[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O>>[CH:16]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)([CH3:17])[CH3:15]

参加物

5

反応物 4

HCID 6362Isopropyl iodideHCID 6853FluoreneHCID 10219674L-AltroseHCID 178418339Butyllithium

生成物 1

HCID 186969H-Fluorene, 9-(1-methylethyl)-

実験手順

Fluorene (15.0 g, 90.4 mmol), n-BuLi (48.1 ml, 120 mmol, 2.5 M in hexane), RX=2-iodopropane (14.0 ml, 139.6 mmol). 42 was isolated as a yellowish solid (18.7 g, quant.). The analytical data were identical with these to be found in the literature (M. A. Schmidt, H. G. Alt, W. Milius, J. Organomet. Chem. 1996, 525, 15).

後処理

  1. custom42 was isolated as a yellowish solid (18.7 g, quant.)

出典と根拠

ORDレコード
ord-1e83d68f28a54b908502277d24e24173
出典データセット
uspto-grants-2015_03
特許番号
US08969624B2

反応ノート

読み込み中…