関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 4,6-Dichloropyrimidine | HCID 70943 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-(6-Chloropyrimidin-4-yl)morpholine | HCID 796070 | — |
反応手順
45.0 g (302.1 mmol) 4,6-dichloropyrimidine are initially introduced into 450 ml water. 26.3 g (302.1 mmol) morpholine are added and the mixture is stirred at 90° C. for 16 h. Thereafter, it is cooled to 0° C. and the precipitate formed is filtered off. The precipitate is washed once with 50 ml water and dried in air.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08987261B2 |
|---|
| 出典データセット | uspto-grants-2015_03 |
|---|
| ORD ID | ord-b2b24157349e445d9ebbf6add1643c01 |
|---|
| 出典メモ | uspto-grants-2015_03 |
|---|
