Diisopropylethylamine → tert-Butyl(+/-)-1-{3-[(cyclopentyl{4-[(4-fluoro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-methyl]phenyl}acetyl)amino]benzyl}cyclopropanecarboxylate

反応式

[NH2:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[CH2:5][C:6]1([C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:8][CH2:7]1.[CH:19]1([CH:24]([C:28]2[CH:33]=[CH:32][C:31]([CH2:34][N:35]3[CH2:43][C:42]4[C:37](=[CH:38][CH:39]=[CH:40][C:41]=4[F:44])[C:36]3=[O:45])=[CH:30][CH:29]=2)[C:25](O)=[O:26])[CH2:23][CH2:22][CH2:21][CH2:20]1.CCN(C(C)C)C(C)C.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F>CN(C=O)C.O>[CH:19]1([CH:24]([C:28]2[CH:33]=[CH:32][C:31]([CH2:34][N:35]3[CH2:43][C:42]4[C:37](=[CH:38][CH:39]=[CH:40][C:41]=4[F:44])[C:36]3=[O:45])=[CH:30][CH:29]=2)[C:25]([NH:1][C:2]2[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=2)[CH2:5][C:6]2([C:9]([O:11][C:12]([CH3:15])([CH3:13])[CH3:14])=[O:10])[CH2:8][CH2:7]2)=[O:26])[CH2:23][CH2:22][CH2:21][CH2:20]1