4-Methyl-3-(trifluoromethyl)benzoic acid → HCID 60197696、化合物

HRID 878084

反応式

HRID 878084 の反応式
[CH3:1][NH:2][C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15].[CH3:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]([OH:23])=O)=[CH:19][C:18]=1[C:26]([F:29])([F:28])[F:27]>>[CH3:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]([N:2]([CH3:1])[C:3]2[CH:4]=[N:5][CH:6]=[CH:7][C:8]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:15])=[O:23])=[CH:19][C:18]=1[C:26]([F:29])([F:28])[F:27]

参加物

3

反応物 2

HCID 27755924-Methyl-3-(trifluoromethyl)benzoic acidHCID 18403336N-methyl-4-o-tolylpyridin-3-amine

生成物 1

HCID 60197696HCID 60197696、化合物

実験手順

The title compound was prepared in analogy to example 90, from N-methyl-4-o-tolylpyridin-3-amine (example 1, intermediate a) and 4-methyl-3-trifluoromethyl-benzoic acid (CAS RN 261952-01-6) after a reaction time of 90 hours. Grey solid (32%). MS (ESI): m/z=385.15 [M+H]+.

出典と根拠

ORDレコード
ord-f0848890fd14425ca24be45b1ff70017
出典データセット
uspto-grants-2015_03
特許番号
US08987307B2

関連ノート

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