Dichlorobenzyl chloride → HCID 68184280、化合物

HRID 878997

反応式

HRID 878997 の反応式
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:11])=[N:7][NH:8]2)=[CH:4][CH:3]=1.[Cl:12][C:13]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15]Cl.C(N1C2C(=CC=C(C(O)=O)C=2)C=C1)C1C=CC=CC=1>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:11])=[N:7][N:8]2[CH2:15][C:14]2[CH:17]=[CH:18][CH:19]=[C:20]([Cl:21])[C:13]=2[Cl:12])=[CH:4][CH:3]=1

参加物

4

反応物 3

HCID 76790Dichlorobenzyl chlorideHCID 179478751-Benzyl-1H-indole-6-carboxylic acidHCID 178434209HCID 178434209、化合物

生成物 1

HCID 68184280HCID 68184280、化合物収率 85.5%

実験手順

The titled compound (228 mg) as a white solid was prepared from the 6-bromo-3-methyl-1H-indazole (152 mg) obtained with the method described in the document (JP 2009-528363 W) and 2,3-dichlorobenzyl chloride (215 mg) according to the method of the process (1) of Example 66.

後処理

  1. customobtained with the method

出典と根拠

ORDレコード
ord-3197af0bf3864058b1276d64180ca859
出典データセット
uspto-grants-2015_03
特許番号
US08987473B2

関連ノート

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