HCID 86700409、化合物 → HCID 86700408、化合物

HRID 879594ノート

反応式

HRID 879594 の反応式
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[CH2:16][NH:15][C:14](=O)[CH2:13][O:12]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1>C1COCC1>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[O:12][CH2:13][CH2:14][NH:15][CH2:16]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1

参加物

3

反応物 1

HCID 86700409HCID 86700409、化合物

生成物 1

HCID 86700408HCID 86700408、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To a solution of 6-(1-methyl-1H-indazol-5-yl)morpholin-3-one (17.8 mg, 0.077 mmol) in THF was added BH3 in THF (1M, mmol). The resulting mixture was stirred at room temperature for 10 hr. The crude compound was evaporated to dryness and used for the next step without further purification. LCMS-ESI+: calc'd for C12H15N3O: 218.1 (M+H+); found: 218.2 (M+H+).

後処理

  1. customThe crude compound was evaporated to dryness
  2. customused for the next step without further purification

出典と根拠

ORDレコード
ord-af3458411c5147519def525373ce9cb5
出典データセット
uspto-grants-2015_03
特許番号
US08987250B2

反応ノート

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