Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 879892

反応式

HRID 879892 の反応式
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

生成物 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vaccuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

後処理

  1. customSolvents were evaporated
  2. customdried under vaccuo

出典と根拠

ORDレコード
ord-a278cc7d859c47cfa5722c2190158b6e
出典データセット
uspto-grants-2015_03
特許番号
US08987295B2

関連ノート

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