Trifluoroacetic acid → 2-Amino-8-fluoro-3-methyl-1-oxo-1,2-dihydro-isoquinoline-4-carboxylic acid [(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-amide
反応式
C1([C@H](NC(C(C2C=CC=C(F)C=2C(O)=O)C(=O)C)=O)C2C=CC=C(F)C=2)CCC1.C(OC(C)(C)C)(=O)NN.C(OC(=O)[NH:45][N:46]1[C:55]([CH3:56])=[C:54]([C:57](=[O:71])[NH:58][C@@H:59]([CH:67]2[CH2:70][CH2:69][CH2:68]2)[C:60]2[CH:65]=[CH:64][CH:63]=[C:62]([F:66])[CH:61]=2)[C:53]2[C:48](=[C:49]([F:72])[CH:50]=[CH:51][CH:52]=2)[C:47]1=[O:73])(C)(C)C.C(O)(C(F)(F)F)=O>C1C=CC=CC=1.ClCCCl>[CH:67]1([C@H:59]([NH:58][C:57]([C:54]2[C:53]3[C:48](=[C:49]([F:72])[CH:50]=[CH:51][CH:52]=3)[C:47](=[O:73])[N:46]([NH2:45])[C:55]=2[CH3:56])=[O:71])[C:60]2[CH:65]=[CH:64][CH:63]=[C:62]([F:66])[CH:61]=2)[CH2:70][CH2:69][CH2:68]1参加物
7
反応物 4
HCID 6422Trifluoroacetic acid
HCID 70091tert-Butyl carbazate
HCID 577333962-(1-{[(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-carbamoyl}-2-oxo-propyl)-6-fluoro-benzoic acid
HCID 67297917(4-{[(S)-Cyclobutyl-(3-fluoro-phenyl)-methyl]-carbamoyl}-8-fluoro-3-methyl-1-oxo-1H-isoquinolin-2-yl)-carbamic acid tert-butyl ester生成物 1
