(E)-(2S)-2-Amino-5-phenyl-hex-4-en-1-ol → (2S)-2-Amino-5-phenyl-hexan-1-ol
反応式
[NH2:1][C@@H:2]([CH2:5]/[CH:6]=[C:7](/[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)\[CH3:8])[CH2:3][OH:4]>CO.[Pd]>[NH2:1][C@@H:2]([CH2:5][CH2:6][CH:7]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH3:8])[CH2:3][OH:4]参加物
4
実験手順
To a solution of (E)-(2S)-2-amino-5-phenyl-hex-4-en-1-ol (180 mg) in methanol (25 ml) at room temperature was added 10% palladium on charcoal (50 mg). The mixture was stirred under an atmosphere of hydrogen (1 atm) at room temperature for 2 h. The catalyst was removed by filtration and the filtrate was concentrated in vacuo to yield a colourless oil, (160 mg, 88%); MS (ISP): 194.3 ([M+H]+).
後処理
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated in vacuo
- customto yield a colourless oil, (160 mg, 88%)
出典と根拠
- ORDレコード
- ord-0262c16c0aa04030bbe5124c79341850
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08242153B2
反応ノート
読み込み中…