反応式
[F:1][C:2]1[CH:3]=[C:4]([NH2:9])[C:5]([NH2:8])=[CH:6][CH:7]=1.[CH2:10](OC(OCC)OCC)C>C(O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]2[N:8]=[CH:10][NH:9][C:4]=2[CH:3]=1参加物
4
反応条件
- 温度
- 150 °C
実験手順
To the solution of 4-fluoro-benzene-1,2-diamine (10 g, 79.4 mmol) and triethylorthoformate (117 mL, 793 mmol) was added few drop of ethanol and the reaction mixture was refluxed at 150° C. overnight. The reaction mixture was concentrated and the residue was directly taken to the next step. [M+H]=137.
後処理
- concentrationThe reaction mixture was concentrated
出典と根拠
- ORDレコード
- ord-55385f5e23674ed5a2bf3443147fd061
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08247418B2
関連ノート
読み込み中…