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2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine → 2-Chloro-4-[1-(2,2-difluoro-ethyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine | HCID 21985391 | — |
| 反応物 | 1H-Imidazole, 1-(2,2-difluoroethyl)-4-iodo-2-methyl- | HCID 21985393 | — |
| 生成物 | 2-Chloro-4-[1-(2,2-difluoro-ethyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine | HCID 11289031 | — |
反応手順
The title compound, MS: m/e=282.0 (M+H+), was prepared in accordance with the general method of example A, step 2, from 2-chloro-4-trimethylsilanylethynyl-pyridine and 1-(2,2-difluoro-ethyl)-4-iodo-2-methyl-1H-imidazole.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091222B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-f3776236429f4aeb87a7c0b85091fbfc |
| 出典メモ | uspto-grants-2006_08 |