Carbon Dioxide → 1-t-Butylimidazole

HRID 888269ノート

反応式

HRID 888269 の反応式
C=O.[C:3](N)([CH3:6])([CH3:5])[CH3:4].C(=O)([O-])[O-].[NH4+:12].[NH4+:13].[CH:14]([CH:16]=O)=O.[C:18](=O)=O>CO>[C:3]([N:12]1[CH:16]=[CH:14][N:13]=[CH:18]1)([CH3:6])([CH3:5])[CH3:4]

参加物

7

反応物 5

HCID 280Carbon DioxideHCID 712FormaldehydeHCID 6385Tert-ButylamineHCID 7860GlyoxalHCID 517111Ammonium Carbonate

生成物 1

HCID 1426651-t-Butylimidazole

試薬・触媒・溶媒 1

HCID 887Methanol溶媒3 回

実験手順

0.62 mol of paraformaldehyde (18.600 g) is initially charged in 80 ml of methanol. 0.6 mol of tertbutylamine (43.884 g, 63.32 ml) in 80 ml of methanol is cautiously added dropwise thereto with ice cooling. At a temperature of 0° C., 0.3 mol of ammonium carbonate (28.820 g) and 0.6 mol of 40% glyoxal solution (87.040 g, 68.8 mol) in 160 ml of methanol are added. Thereafter, the reaction mixture is warmed to room temperature and stirred overnight, in order that the carbon dioxide formed can escape. Ultimately, the solvent is removed and the product is distilled through a column under high vacuum.

後処理

  1. customformed can
  2. customUltimately, the solvent is removed
  3. distillationthe product is distilled through a column under high vacuum

出典と根拠

ORDレコード
ord-6d3c87786b924e73982ac11738e3ea10
出典データセット
uspto-grants-2012_08
特許番号
US08247574B2

反応ノート

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