3-Isopropenyl-5-(5-methylpyridin-2-yl)benzoic acid → 3-Isopropyl-5-(5-methylpyridin-2-yl)benzoic acid
反応式
[C:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:7]([OH:9])=[O:8])([CH3:3])=[CH2:2].[H][H]>C(O)C.[Pd]>[CH:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:7]([OH:9])=[O:8])([CH3:3])[CH3:2]参加物
5
実験手順
To a solution of 3-isopropenyl-5-(5-methylpyridin-2-yl)benzoic acid (150 mg, 0.592 mmol) in ethanol (11.8 mL) was added 10% palladium on carbon (50.0 mg, 0.047 mmol) and the mixture was placed under 1 atm of hydrogen. After 1 h, filtration and concentration gave the crude title compound (150 mg). MS 256.2 (M+1).
後処理
- filtrationfiltration and concentration
出典と根拠
- ORDレコード
- ord-e39aa2da1d1246808d1f71cb8338f589
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08247401B2
反応ノート
読み込み中…