Hydrochloric Acid → 2-Ethylcyclohexylisocyanate

HRID 890366

反応式

HRID 890366 の反応式
[CH2:1]([CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[NH2:9])[CH3:2].Cl.[C:11](Cl)(Cl)=[O:12]>CO>[CH2:1]([CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[N:9]=[C:11]=[O:12])[CH3:2]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 6371PhosgeneHCID 5448542-Ethylcyclohexan-1-amine

生成物 1

HCID 222509222-Ethylcyclohexylisocyanate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

反応条件

温度
110 °C

実験手順

To a solution of 2-ethylcyclohexylamine (0.61 mmol) in methanol was added HCl (4.0 M in dioxane, 0.152 mL), and concentrated to give a residue. Phosgene solution (20% in toluene, 6.0 mL) was added, and the reaction was heated at 110° C. overnight. Toluene and excess of phosgene were removed in vacuo to give a residue.

後処理

  1. concentrationconcentrated
  2. customto give a residue
  3. customToluene and excess of phosgene were removed in vacuo
  4. customto give a residue

出典と根拠

ORDレコード
ord-0f7d26ca9bd248889f2a788c0d2faa80
出典データセット
uspto-grants-2006_02
特許番号
US06995269B2

関連ノート

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