Acetic Acid → N-Acetyl-L-alanine

HRID 890688

反応式

HRID 890688 の反応式
[NH2:1][CH:2]([C:4]([OH:6])=[O:5])[CH3:3].[C:7](O)(=[O:9])[CH3:8].C(OC(=O)C)(=O)C>C(OCC)(=O)C>[C:7]([NH:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3])(=[O:9])[CH3:8]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 602DL-alanineHCID 7918Acetic Anhydride

生成物 1

HCID 88064N-Acetyl-L-alanine

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

反応条件

温度
100 °C

実験手順

134 g (1.50 mol) of DL-alanine are introduced into acetic acid and treated dropwise with 230 g (2.25 mol) of acetic anhydride. The mixture is additionally stirred at 100° C. for 2 h to complete the reaction and the solvent is then stripped off in vacuo. The solid obtained is suspended in ethyl acetate and filtered off with suction. For purification, the solid is washed several times with diethyl ether.

後処理

  1. customthe reaction
  2. customThe solid obtained
  3. filtrationfiltered off with suction
  4. customFor purification
  5. washthe solid is washed several times with diethyl ether

出典と根拠

ORDレコード
ord-7a7506be6c624ae69389ab1b1fb4279d
出典データセット
uspto-grants-2006_02
特許番号
US06998402B2

関連ノート

読み込み中…