Benzaldehyde → 5-Benzylidene-2,4-thiazolidinedione
反応式
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:9]1[CH2:13][C:12](=[O:14])[NH:11][C:10]1=[O:15]>N1C=CC=CC=1.CN(C)C=O.CCCCCC.O>[C:2]1([CH:1]=[C:13]2[S:9][C:10](=[O:15])[NH:11][C:12]2=[O:14])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
7
反応条件
- 温度
- 55 °C
実験手順
Benzaldehyde (0.78 mol, 82.8 g) and 2,4-thiazolidinedione (0.85 mol, 100 g) were heated to reflux in a mixture of pyridine (215 ml) and dimethylformamide (400 ml) for 18 hours. The reaction mixture was cooled to 55° C. and diluted with hexane (360 ml) and water (900 ml) and stirred for 1 hour after cooling to room temperature. The product was collected to afford 175 g of pale yellow solid; m.p. 246°-248° C.
後処理
- temperatureafter cooling to room temperature
- customThe product was collected
出典と根拠
- ORDレコード
- ord-9d7197d11b224038a55a54a8f9b98ee7
- 出典データセット
- uspto-grants-1992_06
- 特許番号
- US05120754
反応ノート
読み込み中…