Methanol → 4-(2-Methoxyethyl)phenol

HRID 893431

反応式

HRID 893431 の反応式
CO[C:3](OC)([C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1)[CH:4]=[O:5].[CH3:15]O>>[CH3:15][O:5][CH2:4][CH2:3][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1

参加物

3

反応物 2

HCID 887MethanolHCID 197888474-Hydroxyphenylglyoxal dimethyl acetal

生成物 1

HCID 925164-(2-Methoxyethyl)phenol収率 47%

実験手順

The procedure of Example 2 was repeated with a solution of 2.00 g (10.2) mmol) 4-hydroxyphenylglyoxal dimethyl acetal in 10 g methanol containing 0.37 g (10.2 mmol) hydrogen chloride and a 0.20 g dry 10% Pd/C catalyst being reacted with hydrogen gas pressurized at 50 psig at 25° C. A 47% yield of 4-(2'-methoxyethyl)phenol was obtained.

後処理

  1. dry with materiala 0.20 g dry 10% Pd/C catalyst
  2. custombeing reacted with hydrogen gas
  3. custompressurized at 50 psig at 25° C

出典と根拠

ORDレコード
ord-d12f1b3bc7654c74aa26163577d4b7bc
出典データセット
uspto-grants-1992_06
特許番号
US05124489

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