Ethylenediamine → N-(2-aminoethyl)-1,2,3,4-tetrahydrobenzo[b]thieno[2,3-c]pyridine-3-carboamide

HRID 893857

反応式

HRID 893857 の反応式
C(OC([CH:8]1[S:20][C:11]23[CH:19]=[CH:18][CH:17]=[CH:16][C:12]2=[N:13][CH2:14][CH2:15][CH:10]3[CH:9]1[C:21]([OH:23])=O)=O)(C)(C)C.[CH2:24]([NH2:27])[CH2:25][NH2:26]>>[NH2:26][CH2:25][CH2:24][NH:27][C:21]([CH:9]1[CH:10]2[C:11]3([CH:19]=[CH:18][CH:17]=[CH:16][C:12]3=[N:13][CH2:14][CH2:15]2)[S:20][CH2:8]1)=[O:23]

参加物

3

反応物 2

HCID 3301EthylenediamineHCID 699596062-Tert-butoxycarbonyl-1,2,3,4-tetrahydro-benzo[b]thieno[2,3-c]pyridine-3-carboxylic acid

生成物 1

HCID 69959178N-(2-aminoethyl)-1,2,3,4-tetrahydrobenzo[b]thieno[2,3-c]pyridine-3-carboamide収率 54%

実験手順

By following the same procedure as above using 0.32 g of 2-tert-butoxycarbonyl-1,2,3,4-tetrahydrobenzo[b]thieno[2,3-c]pyridine-3-carboxylic acid and ethylenediamine as the starting materials, 0.19 g (yield of 54%) of N-(2-aminoethyl)-1,2,3,4-tetrahydrobenzo[b]thieno[2,3-c]pyridine-3-carboamide.di-hydrochloride was obtained (see Table 9-1, Table 10-1).

出典と根拠

ORDレコード
ord-3ca250e19e0043788808b1b01fc60b0c
出典データセット
uspto-grants-1992_06
特許番号
US05126448

関連ノート

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