Sodium Chloride → 2-Ethyl-4-hydroxy-3-methylcyclopent-2-en-1-one
反応式
[CH3:1][C:2]1([O:12]C)[C:6]([CH2:7][CH3:8])=[C:5]([CH3:9])[CH:4]([O:10]C)O1.O1CCCC1.[Cl-].[Na+]>O>[CH3:9][C:5]1[CH:4]([OH:10])[CH2:1][C:2](=[O:12])[C:6]=1[CH2:7][CH3:8]参加物
5
実験手順
2,4-Dimethyl-3-ethyl-2,5-dimethoxy-2,5-dihydrofuran (9.3 g) was added to a mixture of 100 ml of a buffer solution (pH 5; prepared from potassium hydrogen phthalate and sodium hydrogen carbonate) and tetrahydrofuran (50 ml), and the mixture was refluxed for 1 hour. The reaction solution was poured into water, saturated with sodium chloride and extracted three times with ethyl acetate. The ethyl acetate layer was concentrated, and the residue was distilled to obtain 4.3 g of 2-methyl-3-ethyl-cyclopent-2-en-4-on-1-ol.
後処理
- temperaturethe mixture was refluxed for 1 hour
- extractionextracted three times with ethyl acetate
- concentrationThe ethyl acetate layer was concentrated
- distillationthe residue was distilled
出典と根拠
- ORDレコード
- ord-75fc78cc14cf4bab81760dcb3c3a2fe1
- 出典データセット
- uspto-grants-1981_08
- 特許番号
- US04282372
反応ノート
読み込み中…