Thionyl Chloride → 7,8-Dihydroxychromone-3-carbonyl chloride

HRID 895007ノート

反応式

HRID 895007 の反応式
[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13](O)=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1.S(Cl)([Cl:19])=O>>[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13]([Cl:19])=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 127658447,8-Dihydroxychromone-3-carboxylic acid

生成物 1

HCID 130830427,8-Dihydroxychromone-3-carbonyl chloride

実験手順

A mixture of 7,8-dihydroxychromone-3-carboxylic acid (6.6 g, 30 mmol) and thionyl chloride (25 ml) was refluxed for one hour, and the thionyl chloride was removed. After the addition of benzene to the residue, the mixture was evaporated to dryness and the residue was triturated with n-hexane to give the desired compound (7.2 g).

後処理

  1. temperaturewas refluxed for one hour
  2. customthe thionyl chloride was removed
  3. additionAfter the addition of benzene to the residue
  4. customthe mixture was evaporated to dryness
  5. customthe residue was triturated with n-hexane

出典と根拠

ORDレコード
ord-602cf728945244e888a8c3d8c9278467
出典データセット
uspto-grants-1981_08
特許番号
US04285941

反応ノート

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