2-Methyl-6-nitrophenol → 6-Amino-o-cresol

HRID 897717

反応式

HRID 897717 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([N+:8]([O-])=O)[C:3]=1[OH:11].NC1C=CC=C(Cl)C=1O>>[NH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[OH:11]

参加物

3

反応物 2

HCID 831032-Methyl-6-nitrophenolHCID 64860252-Amino-6-chlorophenol

生成物 1

HCID 4136576-Amino-o-cresol

実験手順

2-amino-6-methylphenol was prepared from 2-methyl-6-nitrophenol (0.500 g, 3.26 mmol) in a manner similar to that described for 2-amino-6-chlorophenol. The compound was formed as a black solid (0.030 g, 8%). RP-HPLC (25 to 100% CH3CN in 0.1 N aqueous ammonium acetate over 10 min at 1 mL/min using a Hypersil HS C18, 100 Å, 5 μm, 250×4.6 mm column) tr=5.78 min., 86%; m/z 123 (MH+).

出典と根拠

ORDレコード
ord-746ca0b39d004ca6994778eb64e4c805
出典データセット
uspto-grants-2005_07
特許番号
US06921763B2

関連ノート

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