Triethylamine → N'-hydroxynonanimidamide
反応式
[CH2:1]([C:9]#[N:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Cl.[NH2:12][OH:13].C(N(CC)CC)C>CCO>[OH:13][NH:12][C:9](=[NH:10])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]参加物
5
実験手順
Octyl cyanide (2 g, 14 mmol) and hydroxylamine hydrochloride (2.495 g, 36 mmol) were dissolved in EtOH (10 mL) and treated with triethylamine (5 mL, 36 mmol) at reflux over night. Extraction: AcOEt/water. Silica gel chromatography: heptane/AcOEt 1:2 afforded a white solid (0.65 g, 26%). MS: m/z=173 (M +H).
後処理
- temperatureat reflux over night
- extractionExtraction
出典と根拠
- ORDレコード
- ord-344e2ede1a55402092f36b2c52f6ed11
- 出典データセット
- uspto-grants-2008_04
- 特許番号
- US07351700B2
反応ノート
読み込み中…