Triethylamine → N'-hydroxynonanimidamide

HRID 898118

反応式

HRID 898118 の反応式
[CH2:1]([C:9]#[N:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Cl.[NH2:12][OH:13].C(N(CC)CC)C>CCO>[OH:13][NH:12][C:9](=[NH:10])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 16715NonanenitrileHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 5074022N'-hydroxynonanimidamide収率 27%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Octyl cyanide (2 g, 14 mmol) and hydroxylamine hydrochloride (2.495 g, 36 mmol) were dissolved in EtOH (10 mL) and treated with triethylamine (5 mL, 36 mmol) at reflux over night. Extraction: AcOEt/water. Silica gel chromatography: heptane/AcOEt 1:2 afforded a white solid (0.65 g, 26%). MS: m/z=173 (M +H).

後処理

  1. temperatureat reflux over night
  2. extractionExtraction

出典と根拠

ORDレコード
ord-344e2ede1a55402092f36b2c52f6ed11
出典データセット
uspto-grants-2008_04
特許番号
US07351700B2

関連ノート

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