3-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-ol → 3-(2-Chloro-4-nitro-phenyl)-propan-1-ol

HRID 898553ノート

反応式

HRID 898553 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]#[C:12][CH2:13][OH:14].[H][H]>[Ni].C1COCC1>[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[CH2:11][CH2:12][CH2:13][OH:14]

参加物

5

反応物 2

HCID 230064163-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-olHCID 178418361HCID 178418361、化合物

生成物 1

HCID 688779703-(2-Chloro-4-nitro-phenyl)-propan-1-ol

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A suspension of 1.25 g (6.808 mmol) 3-(2-chloro-4-nitro-phenyl)-prop-2-yn-1-ol and 1.00 g Raney nickel in 50 mL THF was hydrogenated for 12 h at RT and 25 psi hydrogen pressure. The catalyst was filtered off and the filtrate was evaporated down i. vac.

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated down i

出典と根拠

ORDレコード
ord-09c178bafa9f4658a483d396244039d4
出典データセット
uspto-grants-2008_04
特許番号
US07351719B2

反応ノート

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