Benzenamine hydrochloride (1:1) → HCID 73828564、化合物

HRID 903113ノート

反応式

HRID 903113 の反応式
[Na].[CH:2]([CH:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])=O.Cl.[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CO>[NH:12]([CH:2]=[C:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

5

反応物 3

HCID 8870Benzenamine hydrochloride (1:1)HCID 5360545SodiumHCID 21541183HCID 21541183、化合物

生成物 1

HCID 73828564HCID 73828564、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

74 parts of 75 percent pure sodium salt of α-formyl-β-formylaminopropionitrile are refluxed for 1 hour with 58.3 parts of aniline hydrochloride in 400 parts by volume of methanol, the reaction mixture is filtered, and the filtrate is concentrated to half its volume. 59.6 parts of α-anilinomethylene-β-formylaminopropionitrile are obtained, followed by a further 6.3 parts after concentrating the mother liquor; this corresponds in total to 87.4% of theory, based on the Na salt.

後処理

  1. filtrationthe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated to half its volume

出典と根拠

ORDレコード
ord-79db62d71d8946faa78544ea0cdfc50e
出典データセット
uspto-grants-1980_10
特許番号
US04226799

反応ノート

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