2-Amino-2-methyl-1-propanol → N-(2-hydroxy-1,1-dimethylethyl)-2-(isopropyl)-5-methylcyclohexanecarboxamide

HRID 903314ノート

反応式

HRID 903314 の反応式
[CH:1]1([CH3:13])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([C:10](Cl)=[O:11])[CH2:2]1.[NH2:14][C:15]([CH3:19])([CH3:18])[CH2:16][OH:17]>>[CH3:18][C:15]([NH:14][C:10]([CH:3]1[CH:4]([CH:7]([CH3:9])[CH3:8])[CH2:5][CH2:6][CH:1]([CH3:13])[CH2:2]1)=[O:11])([CH3:19])[CH2:16][OH:17]

参加物

3

反応物 2

HCID 118072-Amino-2-methyl-1-propanolHCID 13734319Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-

生成物 1

HCID 3016105N-(2-hydroxy-1,1-dimethylethyl)-2-(isopropyl)-5-methylcyclohexanecarboxamide

実験手順

p-Menth-3-oyl chloride (3.0 g.) was reacted with 2-amino-2-methyl-propan-1-ol (3.0 g.) according to the procedure of Example 3. Product N-(1,1-dimethyl-2-hydroxyethyl)-p-menthane-3-carboxamide was obtained as a crystalline solid which was recrystallised from aqueous methanol. M.p. 123°.

出典と根拠

ORDレコード
ord-be7e031302f244bbb8a67aadd29a16f3
出典データセット
uspto-grants-1980_10
特許番号
US04226988

反応ノート

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