Acetic Anhydride → (Z,Z)-11,13-Hexadecadienal

HRID 903497

反応式

HRID 903497 の反応式
[CH2:1]([OH:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\[CH:13]=[CH:14]/[CH2:15][CH3:16].C(OC(=O)C)(=O)C>N1C=CC=CC=1.C(=O)(O)[O-].[Na+]>[CH:1](=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\[CH:13]=[CH:14]/[CH2:15][CH3:16]

参加物

5

反応物 2

HCID 7918Acetic AnhydrideHCID 536556311,13-Hexadecadien-1-ol, (11Z,13Z)-

生成物 1

HCID 6436739(Z,Z)-11,13-Hexadecadienal

試薬・触媒・溶媒 2

HCID 1049Pyridine溶媒HCID 516892Sodium Bicarbonate溶媒

実験手順

(11Z,13Z)-11,13-hexadecadien-1-ol (3.19 mmol) and acetic anhydride (6.38 mmol), in 5 ml of dry pyridine, are stirred under nitrogen at room temperature for 20 hours. The reaction mixture is then poured in sodium bicarbonate solution and extracted with pentane (2X). The organic layer is washed with dilute HCl and with brine, dried over magnesium sulfate and the solvent removed in vacuo. The crude product is purified to yield the final product, (11Z,13Z)-11,13-hexadecadien-1-al.

後処理

  1. extractionextracted with pentane (2X)
  2. washThe organic layer is washed with dilute HCl and with brine
  3. dry with materialdried over magnesium sulfate
  4. customthe solvent removed in vacuo
  5. customThe crude product is purified

出典と根拠

ORDレコード
ord-904733ac283b49fcabdacd2e6817bb08
出典データセット
uspto-grants-1980_10
特許番号
US04228093

関連ノート

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