Triethylamine → 122570-36-9

HRID 903584

反応式

HRID 903584 の反応式
Cl.[NH2:2][CH2:3][CH2:4][C:5]1[CH:12]=[CH:11][C:9]([OH:10])=[C:7]([OH:8])[CH:6]=1.[C:13]([NH:16][C@H:17]([C:22](O)=[O:23])[CH2:18][CH2:19][S:20][CH3:21])(=[O:15])[CH3:14].C(N(CC)CC)C>CN(C)C=O>[C:13]([NH:16][C@H:17]([C:22]([NH:2][CH2:3][CH2:4][C:5]1[CH:12]=[CH:11][C:9]([OH:10])=[C:7]([OH:8])[CH:6]=1)=[O:23])[CH2:18][CH2:19][S:20][CH3:21])(=[O:15])[CH3:14]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 65340Dopamine HydrochlorideHCID 448580N-acetyl-L-methionine

生成物 1

HCID 22812625122570-36-9

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

2.85 g of dopamine hydrochloride, 4.32 g of N-hydroxysuccinimide ester of N-acetyl-L-methionine, 3.04 g of triethylamine and 15 ml of dimethylformamide are treated in the same manner as described in Example 5. After the reaction, the mixture is condensed under reduced pressure to remove solvent. The residue is dissolve in ethyl acetate, washed with water and dried. The solution is condensed to remove solvent. 3.1 g of N-(N-acetyl-L-methionyl)-dopamine are obtained as caramel.

後処理

  1. customAfter the reaction
  2. customcondensed under reduced pressure
  3. customto remove solvent
  4. dissolutionThe residue is dissolve in ethyl acetate
  5. washwashed with water
  6. customdried
  7. customcondensed
  8. customto remove solvent

出典と根拠

ORDレコード
ord-6823c088a7c342818f6492ad5f3a1b94
出典データセット
uspto-grants-1980_10
特許番号
US04228183

関連ノート

読み込み中…