2-(Bromomethyl)benzonitrile → HCID 23333579、化合物

HRID 904189ノート

反応式

HRID 904189 の反応式
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:5][CH:4]=1.C(=O)([O-])O.[Na+].Br[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[C:28]#[N:29]>O>[CH3:1][N:2]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[C:28]#[N:29])[C:3]1[CH:4]=[CH:5][C:6]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 895992-(Bromomethyl)benzonitrileHCID 516892Sodium BicarbonateHCID 11550151N-methyl-4-ethoxycarbonylmethylaniline

生成物 1

HCID 23333579HCID 23333579、化合物収率 112.8%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

N-Methyl-4-ethoxycarbonylmethylaniline (10 g), sodium hydrogencarbonate (5 g), water (5 ml), and 2-bromomethylcyanobenzene (12.2 g) were treated in the same manner as described in Example 1 for the preparation of the starting material. 18 g of N-methyl-N-(2-cyanobenzyl)-4-ethoxycarbonylmethylaniline was obtained as a light-yellow oily material.

後処理

  1. customas described in Example 1 for the preparation of the starting material

出典と根拠

ORDレコード
ord-c1ee446f2a1c4e14988399d4bded4515
出典データセット
uspto-grants-1980_10
特許番号
US04230703

反応ノート

読み込み中…