Quinoline → 3-Buten-2-ol, 1,1-dimethoxy-2-methyl-

HRID 904454ノート

反応式

HRID 904454 の反応式
[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[C:5]#[CH:6].N1C2C(=CC=CC=2)C=CC=1.[H][H]>[Pd]>[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[CH:5]=[CH2:6]

参加物

5

反応物 3

HCID 7047QuinolineHCID 128752274,4-Dimethoxy-3-methyl-but-1-yn-3-olHCID 178418361HCID 178418361、化合物

生成物 1

HCID 110080503-Buten-2-ol, 1,1-dimethoxy-2-methyl-

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

198 G. of 4,4-dimethoxy-3-methyl-but-1-yn-3-ol are dissolved in 960 ml. of high-boiling petroleum ether and, after the addition of 19.35% palladium catalyst and 19.3 g. of quinoline, hydrogenated under normal conditions. After the uptake of 33.5 l. of hydrogen, the hydrogenation is stopped. The catalyst is filtered off. The filtrate is evaporated under reduced pressure. The remaining 4,4-dimethoxy-3-methyl-but-1-en-3-ol boils, after rectification, at 70°-72° C./18 mm Hg.

後処理

  1. filtrationThe catalyst is filtered off
  2. customThe filtrate is evaporated under reduced pressure
  3. customat 70°-72° C.

出典と根拠

ORDレコード
ord-6257e5bac30e416ba14124dd05da3b04
出典データセット
uspto-grants-1980_10
特許番号
US04230872

反応ノート

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