Timonacic → 3-[4-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

HRID 904499

反応式

HRID 904499 の反応式
[CH2:1]([NH:16][C:17]1[CH:34]=[CH:33][C:20]([C:21]([N:23]2[CH:27]([C:28]([O:30]CC)=[O:29])[CH2:26][S:25][CH2:24]2)=[O:22])=[CH:19][CH:18]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].S1CC(C(O)=O)NC1>C(=O)(O)[O-].[Na+].CC(C)=O>[CH2:1]([NH:16][C:17]1[CH:18]=[CH:19][C:20]([C:21]([N:23]2[CH:27]([C:28]([OH:30])=[O:29])[CH2:26][S:25][CH2:24]2)=[O:22])=[CH:33][CH:34]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

参加物

4

反応物 2

HCID 9934TimonacicHCID 536530283-[4-(4-Pentadecenylamino)benzoyl]-4-carboethoxythiazolidine

生成物 1

HCID 538355243-[4-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

試薬・触媒・溶媒 1

HCID 86737261Acetone sodium bicarbonate溶媒

実験手順

By means of the alkaline hydrolysis method of Example 2 the ethyl ester of Example 385 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 385 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

後処理

  1. customThis acid is also prepared

出典と根拠

ORDレコード
ord-a25f4f14ee584281bdb91b5e95b0134e
出典データセット
uspto-grants-1980_10
特許番号
US04230878

関連ノート

読み込み中…