9-(2-cyclohexenyl)-2-propoxy-9H-adenine → 9-Cyclohexyl-2-n-propoxy-9H-adenine
反応式
[CH:1]1([N:7]2[CH:15]=[N:14][C:13]3[C:8]2=[N:9][C:10]([O:17][CH2:18][CH2:19][CH3:20])=[N:11][C:12]=3[NH2:16])[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1>C(O)C.[Pd]>[CH:1]1([N:7]2[CH:15]=[N:14][C:13]3[C:8]2=[N:9][C:10]([O:17][CH2:18][CH2:19][CH3:20])=[N:11][C:12]=3[NH2:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1参加物
4
実験手順
A solution of 2.21 g (7.8 mmoles) of 9-(2-cyclohexenyl)-2-propoxy-9H-adenine in 30 mL of 90% ethanol was hydrogenated overnight with 250 mg of 10% palladium on carbon and then filtered. The filtrate was evaporated in vacuo, giving a residue which was crystallized from ethyl acetate--n-hexane. Yield 1.85 g (76%); melting point 148°-150° C.
後処理
- filtrationfiltered
- customThe filtrate was evaporated in vacuo
- customgiving a residue which
- customwas crystallized from ethyl acetate
出典と根拠
- ORDレコード
- ord-c2d9738041144ff48bc99cb88811306a
- 出典データセット
- uspto-grants-1983_12
- 特許番号
- US04419358
反応ノート
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